Morphogenesis duringXenopusgastrulation requires Wee1-mediated inhibition of cell proliferation
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Morphogenesis during Xenopus gastrulation requires Wee1-mediated inhibition of cell proliferation.
Major developmental events in early Xenopus embryogenesis coincide with changes in the length and composition of the cell cycle. These changes are mediated in part through the regulation of CyclinB/Cdc2 and they occur at the first mitotic cell cycle, the mid-blastula transition (MBT) and at gastrulation. In this report, we investigate the contribution of maternal Wee1, a kinase inhibitor of Cyc...
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ژورنال
عنوان ژورنال: Development
سال: 2004
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00971